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Surface-Enhanced Raman Spectroscopy (SERS) Substrates

Lead Time: 4 weeks

Prices From $84.00

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Product Details

Surface-enhanced Raman spectroscopy (SERS) substrates let you make fast, repeatable measurements for the identification and quantification of SERS-active analytes. Typical applications include trace level detection of narcotics, pesticides and taggants.

Note: The photos shown above are the silver nanoparticle substrates (item RAM-SERS-AG).

Here are some key applications made possible with SERS substrates:

  • Detection of narcotics. Fast identification of drugs in the field is a real boon for those combating drug-related crime. Often only small residues of a sample can be collected from a crime scene. SERS also opens up a potential route for fast roadside drug screening of drivers using saliva samples.
  • Food safety. Certain additives such as melamine found in milk powder can be extremely harmful even at very low concentrations. Using SERS, we can qualify and quantify the level of dangerous trace elements in our food supply chain.
  • Anti-counterfeit tagging. High value products that are subject to duties and taxes — petrol is one example — are often the target of piracy and fraud. By adding a small amount of a SERS-active taggant to the unadulterated product, detecting the taggant becomes an instant indicator of authenticity.


Product Overview

  • High sensitivity -- substrates demonstrate superior sensitivity for a range of analytes 
  • Great stability -- highly stable substrates require no special handling and can be stored at room temperature
  • Reproducibility -- highly reproducible and easily scaled manufacturing methods enable sensitive measurements at an affordable price
  • Customized form factors -- unique production techniques can be tailored to impart specificity to analytes (on demand) and to custom form factors such as swabs and coatings
  • Easy to use -- for great flexibility, substrates work reliably with Ocean Insight Raman instruments
  • Quantity -- sold in packs of 5 substrates

SERS for Trace Level Virus Detection

In this video, we demonstrate how our proprietary surface-enhanced Raman spectroscopy substrates enhance Raman signal to detect antibody samples from SARS-CoV-1 and -2 proteins.

COVID-19 Antibody Detection

In this demo, learn how high-sensitivity SERS substrates can be used for rapid detection of COVID-19 and other virus antibodies. Our solutions enable diagnostic kit developers to drive low limits of viral detection and speed up pass/fail test results.


Select model to see full specifications


Excitation Wavelengths:
532 nm
785 nm
ppm to ppb level sensitivity for wide range of analytes
SERS Active Chemistry:
Gold (Au) Nanoparticles
Silver (Ag) Nanoparticles
Laser Power:
≤20 mW
SERS Active Area:
5.5 mm diameter circle
Slide Dimensions:
25.4 x 76.2 x 1 mm
Slide Material Specification:
Borosilicate Glass
Storage Lifetime:
1 month
1.5 months
Volume Of Analyte:
15 µL

Please visit our FAQs page for information on what chemicals can be detected with Ocean Insight SERS substrates, and at what concentrations.

Measurement techniques