Ocean Insight 2020 Grant Program Winners Announced
- Education & Academia
February 1, 2021
We are pleased to announce the winners of the 2020 Ocean Insight Grant Program.
From improving cancer detection and treatment to addressing issues related to the environment and climate change, our inaugural class of grant winners are using optical sensing technologies to take on challenges for a safer, cleaner, healthier world.
The seven winning proposals were selected from among hundreds of entries representing more than 50 countries and comprising leading universities, research institutions and technology start-ups.
Grantees will be honored at a virtual Ocean Insight Grant Program Awards event, with scheduling and other details to be announced.
Thank you and CONGRATULATIONS to ALL the participants!
Izmir Biomedicine and Genome Center, Izmir, Turkey
Submitted by Arif Engin Cetin
Summary: Improving therapeutic response of cancer patients to drug treatments
Many cancer patients are cured, and their life quality improved, thanks to new treatment options. However, completely curing this disease is very challenging, due to the resistance of cancer cells to drug therapies. To address this, a plasmonic functional assay platform will be developed that can determine therapeutic responses of cancer models at single-cell sensitivity levels.
Traditional techniques determine drug treatments via monitoring the response of patients to such drug treatments; i.e., their decision-making mechanism is very slow. Given the fatality of this disease, making a quick decision is extremely important. The platform will expedite the duration of drug selection for different cancer types, and eliminate unnecessary treatment options, by monitoring responses to a range of drugs simultaneously and all in the same platform. This feature will help doctors choose proper standard-of-care drug therapies with high accuracy, thus increasing the survival rate of patients.
Amplified Sciences, West Lafayette, Indiana, USA
Submitted by Diana Caldwell and Rajesh Ummadisetti, Ph.D.
Summary: Improving pancreatic cancer diagnostics
Pancreatic cancer is the fourth deadliest cancer in the U.S. Early detection is key for patient survival. Pancreatic cysts represent precursors to ductal pancreatic adenocarcinomas presenting a significant risk if undiagnosed. We are developing a novel assay for patients with incidentally detected cysts (1M detected annually) that identifies cancer earlier thus saving lives and improving health by reducing unnecessary surgeries.
Current standard of care competitors are plagued with low accuracy and limitations due to large sample size requirements. We are developing a highly accurate diagnostic that both rules out disease (mucinous vs. non-mucinous) and distinguishes between high and low-grade dysplasia using unprecedented small volumes of fluid. Our chemometric platform also enables the multiplexing of biomarkers (genomic/proteomic/functional markers).
Chalmers University of Technology, Gothenburg, Sweden
Submitted by Santiago Arellano
Summary: Assessing the impact of aerosols and cloud particles on the atmosphere
Despite being present in small amounts, particles have a disproportionally large effect on radiative balance in the atmosphere, where the imbalance causes climate change, or in the quality of air, which has profound effects on human health.
Particles are characterized by composition, shape, size and mass. Information about these characteristics is encoded in the way that particles scatter out radiation and change the polarization of light. Recent progress in spectropolarimetry allows us to build relatively simple systems to obtain general characteristics of particles. We aim at developing such a system with a focus on forest fires and volcanic eruption clouds. They can then be deployed in existing gas monitoring networks, such as NOVAC (led by our group), present in more than 40 volcanoes of the world.
Biko Biolabs, Cambridge, Massachusetts, USA
Submitted by Kelsey Sakimoto
Summary: Breaking down bulk and microplastic waste into carbon feedstock chemicals
Plastic pollution affects both terrestrial and aquatic ecosystems, with ~90% of recyclable plastics entering fragile ecosystems. Our work addresses this problem by providing a scalable, distributed solution to capture in-place and remediate all plastic waste through bulk oxidation, and charts a course toward remediation of persistent microplastics in the environment. The resulting product is a safe, ecologically friendly, biocompatible mixture of organic acids and alcohols.
The resulting plastic-derived mixture can serve as an organic carbon source for sustainable manufacturing through biological fermentation with applications in pharmaceuticals, biomaterials (biopolymers), alternative proteins (cultured meat), and more.
Northwest A&F University, Xianyang, Shaanxi, China
Submitted by Baofeng Su
Summary: Monitoring ecosystems to address environmental deterioration and safety issues
Deterioration of the ecological environment and food safety issues are major issues affecting the sustainable development of the world today. Efficient field ecology and crop monitoring systems play an important role in analyzing environmental changes.
Our plan is to develop a remote monitoring system that combines Ocean Insight sensors and Internet of Things technology, and uploads the remotely acquired spectral data to a cloud server wirelessly. This will reduce labor intensity while making it easier to build a huge ecosystem and food monitoring network, while providing programs and technical support for the development of ecological and food production monitoring based on big data. And provide help for the green, healthy and sustainable development of the world.
Texas A&M University, College Station, Texas, USA
Submitted by Zi Jing Wong
Summary: Developing nanophotonics sensors for coronavirus detection
Conventional optical biosensors are large, non-portable, expensive, and have limited sensitivity due to a small shift of resonant frequency with the virus concentration. In contrast, our nanophotonic sensors exhibit exponential increase in sensitivity. Through the incorporation of coronavirus-targeting bioreceptors in our design, we can realize a highly sensitive COVID-19 viral detector.
The ability to detect coronavirus at an extremely low concentration level enables open space virus detection with unprecedented accuracy. In addition, our sensor is based on an optical waveguide array that can be manufactured on a chip, thus significantly reducing its size, weight, and cost. By combining with Ocean Insight’s low-noise and ultra-compact spectrometer, a truly affordable, portable and high-efficacy coronavirus detector can be envisioned.
Université des Antilles, Schoelcher, France
Submitted by Paule Salvin
Summary: Developing solutions for electrochemical depollution of wetland and aquatic areas
Wetlands and aquatic areas are subject to chemical pollution related to the agricultural and maritime sectors. Research carried out in Martinique is developing solutions to remedy this through: electrochemical depollution of waters in organochlorine compounds, development of eco-compatible substances for anti-corrosion use, and recovery of invasive Sargassum algae.
We are developing an innovative device – a microbial fuel cell -- for the bio-electrochemical depollution of water polluted by pesticides, herbicides and pollutants. This technology is based on the combination of microbial and electrochemical degradation techniques for organic substances. In addition, bio-remediation can be coupled with renewable electricity production.
*Summaries have been edited for length and clarity.
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